Dinitrophenol 2 4 DNP – 2 4 dinitrophenol for weight loss in bodybuilding and fitness dnp

inferno diet pill

Dinitrophenol 2 4 DNP

2 4 dinitrophenol for weight loss in bodybuilding and fitness dnp


DNP s bad……mkay?

The best thing, that may happen to you is temporal weight loss. Yes, temporal – because if you dont learn proper dieting and exercise your bodyfat will eventually return. Your health wont.

The worst thing is death, and it happens every year. There is no cure from DNP poisoning.

But there’s a way! Really. Just read this fucking book.

General info

2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death. – PubMed – NCBI

2,4-Dinitrophenol (DNP) is reported to cause rapid loss of weight, but unfortunately is associated with an unacceptably high rate of significant adverse effects. DNP is sold mostly over the internet under a number of different names as a weight loss/slimming aid. It causes uncoupling of oxidative phosphorylation; the classic symptom complex associated with toxicity of phenol-based products such as DNP is a combination of hyperthermia, tachycardia, diaphoresis and tachypnoea, eventually leading to death. Fatalities related to exposure to DNP have been reported since the turn of the twentieth century. To date, there have been 62 published deaths in the medical literature attributed to DNP. In this review, we will describe the pattern and pathophysiology of DNP toxicity and summarise the previous fatalities associated with exposure to DNP.

General info

Rachael Cook, 25, suffered a cardiac arrest after taking dinitrophenol (DNP)

Slimmer, 25, died after taking controversial ‘rat poison’ diet pill because she was worried she had eaten too much at her birthday dinner
She bought the substance online because she thought losing weight would help her get pregnant, inquest told
She died three days after her birthday, after fearing she had eaten too much at an all-you-can eat celebratory dinner
Doctor tells hearing of drug, ‘you may as well be taking rat poison’

A woman died after taking a controversial diet pill described by one doctor as ‘rat poison’ after worrying that she had eaten too much at her birthday dinner, an inquest heard.

Rachael Cook, 25, from Worthing, West Sussex, had been trying for a baby with her boyfriend and bought the dinitrophenol (DNP) online after being told if she lost weight, it might help her conceive.

An inquest into her death heard how Miss Cook died from a cardiac arrest three days after her birthday, having taken the substance because she feared she had eaten too much at a celebratory trip to an all-you-can eat buffet.

General info

A letter from guest

You say it’s dangerous and then show them how to buy AND USE a drug that has 62 published deaths in the medical literature. You should be sued if one person dies because of this website. One person = one mother, father, grandparents, children, cousins, fiance, girlfriend, boyfriend. You are hurting people with this website and you have a responsibility to take it down. If you don’t, and someone dies, you are at fault. Just because you don’t have a knife doesn’t mean you didn’t commit murder. Gurndingh J. 2,4-dinitorphenol(DNP): a weight loss agent with signficant acut toxicity and risk of DEATH. J Med Toxicol 2011;(3):205-12.

Answer from site admin:
Dear guest! I tried to answer to email you have provided, but this address wasn’t registered in the system, so I’ll just write here.

You are right, but do you really think that closing one site will help saving peoples lives? All I do is provide information on taking DNP the SAFEST way (which is risky anyway).
What most dangerous for people is not knowing, or knowing wrong about how to take this substance.
If you see any adversary content – just let me know, I’ll delete it. This web site is open for any new articles, how about you write some?

DNP users experience

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DNP and Diet Composition for Bodybuilders and Athletes


DNP does not interact directly with any macro- or micronutrients, and so, theoretically, can be used in conjunction with any diet plan imaginable.

Virtually all bodybuilders and athletes who use DNP, however, do so with the same goal: rapid fat loss, with minimal catabolism of muscle protein. For these athletes, a few key points are essential.

Although DNP is surprisingly protein-sparing, the best way to spare muscle protein is also the most obvious way—namely, to eat enough of it.

Athletes should be sure to consume at least 1 to 1.5 grams of protein per pound (= 2 to 3 grams per kg) of bodyweight, regardless of the other particulars of their diet.


As mentioned on the workout page, muscle glycogen depletion shifts the body’s metabolic balance toward lipolysis (fat burning). Therefore, preparatory glycogen depletion—done before DNP supplementation is begun—is highly advisable, especially for athletes who are already lean.

If glycogen is depleted:

In this case, a low-carbohydrate diet will produce maximum fat loss, with the bonus of causing minimal physical discomfort (see below). If carbohydrate cravings occur, stimulants with an appetite-suppressant effect, such as ephedrine or caffeine, may be helpful in combating them.

– For athletes with substantial experience in low-carbohydrate dieting, these cravings may be less intense, or even absent altogether.

– Carbohydrate cravings that persist through the use of stimulants may be a sign that liver glycogen is depleted. In this case, consuming 5 to 15 grams of fructose—which will refill liver glycogen without affecting muscle glycogen—should reduce the intensity of the cravings. Powdered fructose, which can be added to any drink as a sweetener, is ideal. If this is not available, the next-best option is apples or pears, which have the highest ratio of fructose to glucose of all common fruits.

If glycogen is not depleted:

In this case, the body’s metabolic balance is not shifted as far toward lipolysis (fat burning). As a result, greater metabolism of both carbohydrates and protein will occur by default.

– If glycogen is not depleted, the athlete’s diet should not be too low in carbohydrates. If significant glycogen remains in muscle tissue, a carbohydrate intake of less than approximately 1 g/kg (about 0.5 g/lb) of bodyweight may place the athlete at risk for protein catabolism. In this case the body may also deplete blood glucose, placing the athlete at risk for hypoglycemia as well.

– Sufficient protein (see above) will mostly guard against muscle loss, provided that a minimum of carbohydrate is consumed as described above.

– Carbohydrate should come mostly from high-glycemic-index (“slow carb”) foods. This will help the athlete avoid dangerous swings in blood glucose levels as well as the discomfort of excessive heat wasting (see below).

Apart from the considerations above, DNP allows considerable flexibility in the athlete’s diet. Among the other factors to be considered, perhaps the most important is DNP’s “heat wasting” effect.

As described on the chemistry page, DNP does not disrupt glucose metabolism; instead, it causes much of the energy from glucose to be thrown off as heat. As a result, any rapid infusion of glucose into cells will accelerate the rate of heat wasting. Simply put, the consumption of sugars or other “fast” carbohydrates (white rice, refined flour, etc.) will raise heat output significantly.

At lower doses of DNP, then, there are no inherent restrictions on the athlete’s carbohydrate consumption, other than the athlete’s own ability to tolerate the extra heat, sweating, and discomfort. At higher doses, on the other hand, carbohydrate consumption should be monitored carefully to mitigate the risk of hyperthermia.

Dosing for DNP is discussed here.

Learn about the chemistry and action of DNP here.

Information on stacking DNP with other fat burners is here.

Click here to read more about DNP and calorie consumption.

Read about workouts to preserve lean mass here.

General info

DNP and Calorie Consumption

If you’re reading this page, you already know that DNP causes a radical increase in the body’s consumption of calories. (Click here to learn how.)

First, some numbers. It has been estimated that approximately 1 mg/kg bodyweight/day of DNP increases calorie consumption by about 10%. So, for instance, an 80-kg athlete taking 400 milligrams of DNP per day might expect an increase of 800/40 x 10% = 50% in his or her rate of metabolism. That’s 50% more calories burned!

Compared to other pro-lipolytic (fat burning) compounds, there’s no contest. The ephedrine/caffeine stack (“ECA”) increases metabolism by only 1 to 3 percent. Even high doses of clenbuterol (“clen”) cause only a 10% increase, which can only be sustained for a couple of weeks. Used responsibly, DNP can be several times as effective as these more commonly used fat burners.

But the difference doesn’t stop there.

The other fat burners used by bodybuilders (ECA, clen) work by binding to various neurochemical receptors. Simply put, ECA and clen trigger the production of more energy—but that energy is produced just as efficiently as usual. Because the energy production process isn’t affected, there’s no change in the calorie requirement for physical activities, either. In short, ECA and clen effectively add a few calories to an athlete’s energy expenditure, but they don’t multiply that expenditure by anything.

DNP, on the other hand, doesn’t add to an athlete’s energy consumption. DNP multiplies an athlete’s consumption of energy—for everything.

Say an athlete performs enough cardio to burn 300 extra calories (over and above base metabolism) under “normal” conditions.

– With supplemental ECA or clenbuterol, this activity will still burn only 300 extra calories.

– With supplemental DNP, the same activity burns MORE calories. If the dose of DNP is sufficient to produce a 20% increase in metabolism, the activity will now burn 360 extra calories, over and above the original increase provided by DNP. If the dose provides a 50% increase, the activity will burn 450 extra calories. And so on.

Thus, once the caloric effect of DNP has been calibrated for a particular bodybuilder or athlete, the same multiplier applies to all physical activity that he or she performs. Even relatively easy activities, such as walking, can contribute significantly to the athlete’s energy deficit.

Incidentally, this is also the reason why high-dose “inferno” treatment with DNP is generally a bad idea, as also mentioned on the dosing page. At such high doses, DNP will cause so much fatigue that even everyday activities will become difficult to perform. Athletes may find it exhausting just to walk a few blocks, let alone to work out hard enough to retain muscle (click here (LINK TO WORKOUT PAGE for more on preserving muscle on DNP). By sticking with a more moderate DNP dosage and supplementing it with some easy, low-intensity cardio activity, athletes can achieve the same calorie burn as from higher doses, but with less debilitating fatigue, less risk of muscle loss, and, most importantly, a much lower risk of hyperthermia or other toxic effects.

Dosing for DNP is discussed here.

Learn about the chemistry and action of DNP here.

Information on stacking DNP with other fat burners is here.

To read more about the effects of DNP on different bodybuilding diets, click here.

Read about workouts to preserve lean mass here.

General info

How DNP (2,4-dinitrophenol) Works

In technical terms, DNP (2,4-dinitrophenol) is a “classical uncoupler of oxidative phosphorylation”. It works in the mitochondria, the structures that serve as “powerhouses” of all animal cells.

In the presence of oxygen, cells consume glucose. Within the inner membrane of each mitochondrion, the resulting molecules are processed through a series of reactions known as the Krebs cycle. The products of this cycle cause protons (H+) to diffuse through the inner membrane of the mitochondrion, from within the membrane out into the “matrix” (outer region) of the mitochondrion. As a result, a “chemiosmotic gradient”—similar to an electric potential—is produced. To relieve this gradient, the protons are allowed to drift back through the inner mitochondrial membrane.

Normally, the only re-entry point for these protons is through an enzyme known as ATP synthase. When a proton passes through ATP synthase, its energy is used to drive the creation of ATP—the “fuel” of all living cells. Thus, if the membrane is working properly, this drift of protons ensures a steady supply of fuel for the body.

Now, enter 2,4-dinitrophenol (DNP) into the picture.

When DNP is present in the cell, it serves as a “protonophore”: it is able to shuttle protons back into the inner membrane of the mitochondrion. As a result, the protons are able to bypass the action of ATP synthase and simply diffuse back inside the inner membrane. Their energy is not tapped to produce ATP, nor is it used to provide energy for the cell in any other way. It is simply “wasted” as radiated heat.

This heat, incidentally, accounts for the danger posed by acute overdoses of DNP. The body has no natural feedback cycle by which to counteract it, and it increases in proportion to the dosage of DNP administered. Therefore, an acute overdose of DNP can cause dangerous hyperthermia.

Although DNP is a synthetic chemical, there are natural molecules that act as uncouplers in essentially the same way. For instance, the “brown fat” of newborn infants, and the fat of hibernating animals, contain “uncoupling proteins” that produce excess heat in the same way as DNP. As a result, newborns and hibernating animals are protected from hypothermia, to which both would otherwise be extremely vulnerable.

Importantly, DNP does not disrupt any other step in the process of respiration and oxygen consumption. By allowing protons to bypass ATP synthase, DNP makes respiration much less efficient; it also increases oxygen consumption, in much the same way as would cardio exercise. But it leaves the respiratory chain intact.

Dosing for DNP is discussed here.

Information on stacking DNP with other fat burners is here.

Click here to read more about DNP and calorie consumption.

To read more about the effects of DNP on different bodybuilding diets, click here.

Read about workouts to preserve lean mass here.

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